The aim of the present study is to investigate the amount of salt in the Musian plain and its relationship with falling water table during the time span of 2001-2013. To conduct this research, statistics from 7 observation wells were used. Then, the zoning maps of EC, SAR, TH and TDS were drawn. In order to clarify the relationship between these maps and the drop in water table levels, the hydrograph and the groundwater drawdown map of the plain were prepared. The results showed that the observed groundwater drawdown in the plain has led to an increase in all four parameters in the studied area so that EC, TH and TDS have exceeded world standards in most parts of the studied area. Low amount of rainfall in the area, successive drought and ultimately, the existence of Aghajary clastic formations can be mentioned as factors influencing the unfavorable quality of groundwater in the plain.